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proBDNFandp75NTRControlExcitabilityandPersistentFiringofCorticalPyramidalNeurons

发布于：2024-10-09 作者：admin 阅读：1

of (EC) is a key of and 。 We here that a pro-brain- ()- plays a major role in and of in layer V of the EC。 Using , we show that in from wild-type mice but not from -null mice。 , - of and their , and acute to - in of 。

of in or also and , that the - *** to 。 4,5- (PIP2)- play a role in in the EC and we that - PIP2 。 , in and - of PIP2。

, we show that the of by on a -Rac1-PI4K 。 The that and in the *** CNS was in vivo and we that -null mice show in but also an for 。 We that the - axis and to EC with the risk of 。

: of (EC) is for . We here that pro-brain- () to a Rac1- and 4,5-- that . , using loss-of- , we find that or and , that a role of this - may be to in vivo. with this, mice null for show in but also an for . We that by EC , the - the of .

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